MMP2 (HEK293), C-terminal His-tag, human recombinant protein

Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-80213 20 µg - -

3 - 15 business days*

628.00€
 
Human matrix metallo-peptidase-2 (MMP2), also known as gelatinase A (GenBank Accession No.... more
Product information "MMP2 (HEK293), C-terminal His-tag, human recombinant protein"
Human matrix metallo-peptidase-2 (MMP2), also known as gelatinase A (GenBank Accession No. NM_004530), a.a. 30 - 660 (end), with C-terminal His-tag, MW=72 kDa, expressed in an HEK293 cell expression system. Protein function: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-/-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. [The UniProt Consortium]
Keywords: MMP2, CLG4A,
Supplier: BPS Bioscience
Supplier-Nr: 80213

Properties

Application: Enzyme kinetics, inhibitor screening, selectivity profiling
Conjugate: No
Host: Human cells
Species reactivity: human
MW: 72 kD
Purity: >90%
Format: Solution

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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