6 products were found matching "Cay11801-1"!

Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid ethyl ester is a lipophilic derivative of ferulic acid,...

Prostaglandin K1 (PGK1) is a 9,11-diketo analog of PGE1 (Cay-13010) or PGD1 (Cay-12000). It is a PGE2 receptor subtype EP1 agonist that has 387-fold reduced potency compared to PGE2 (Cay-14010).Formal Name: 9,11-dioxo-15S-hydroxy-prost-13E-en-1-oic acid. CAS Number: 69413-73-6. Synonyms: PGK1. Molecular Formula:...

ML-264 is a selective inhibitor of Krüppel-like factor 5 (KLF5), a zinc finger-containing transcription factor that is highly expressed in rapidly dividing intestinal epithelial cells. It displays an IC50 value of 29 nM in a cell-based assay for proliferation of KLF5-expressing DLD-1 cells and an IC50 value of 81 nM...

ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs. It exhibits a 10-fold more potent inhibition of MLCK than its parent compound ML-9 (Cay-10010236).Formal Name:...

INK128 is an inhibitor of TORC1/2, acting as an ATP-dependent inhibitor of mTOR kinase (IC50 = 1 nM). It blocks the phosphorylation of downstream substrates of both TORC1 and TORC2. INK128 interferes with the growth of cell lines which are resistant to rapamycin and pan-PI3K inhibitors. Moreover, daily, oral...

XL147 is an inhibitor of class I PI3Ks (IC50s = 0.039, 0.036, 0.023, and 0.383 µM for p110alpha, -delta, -gamma, and -beta, respectively). It is selective for class I PI3Ks over the class III PI3K vacuolar protein sorting 34 (Vps34, IC50 = 6.974 µM), as well as DNA protein kinase (DNA-PK) and mammalian target of...