ML-090

ML-090
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15172-10 10 mg -

6 - 10 business days*

43.00€
Cay15172-25 25 mg -

6 - 10 business days*

94.00€
Cay15172-50 50 mg -

6 - 10 business days*

156.00€
 
NADPH oxidase 1 (NOX1) generates reactive oxygen species (ROS) in colon epithelial cells that... more
Product information "ML-090"
NADPH oxidase 1 (NOX1) generates reactive oxygen species (ROS) in colon epithelial cells that interacts with both pathogenic and normal bacteria. Excess ROS production, however, is associated with damage to the intestinal mucosa, inflammatory bowel disease, and prostate cancer. ML-090 is the first identified NOX1-specific inhibitor (IC50 = 360 nM in HEK293 cells) based on a quinoxaline scaffold that demonstrates potent selectivity over NOX2, NOX3, and NOX4 (IC50s > 10 µM) and xanthine oxidase (IC50 = 3.5 µM).Formal Name: 5,12-dihydro-quinoxalino[2,3-b]quinoxaline. CAS Number: 531-46-4. Synonyms: CCG-44699, CID-616479, Fluoflavin, NSC 179821. Molecular Formula: C14H10N4. Formula Weight: 234.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Acetonitrile: Slightly Soluble, DMF: Slightly Soluble, DMSO: Slightly Soluble, Ethanol: Slightly Soluble. lambdamax: 248, 324, 341, 393, 415, 442 nm. SMILES: C12=CC=CC=C1N=C3C(NC(C=CC=C4)=C4N3)=N2. InChi Code: InChI=1S/C14H10N4/c1-2-6-10-9(5-1)15-13-14(16-10)18-12-8-4-3-7-11(12)17-13/h1-8H,(H,15,17)(H,16,18). InChi Key: WGKYYZDYHYOKQV-UHFFFAOYSA-N.
Keywords: CCG-44699, CID-616479, Fluoflavin, NSC 179821, 5,12-dihydro-quinoxalino[2,3-b]quinoxaline
Supplier: Cayman Chemical
Supplier-Nr: 15172

Properties

Application: NADPH oxidase 1 (NOX-1) inhibitor
MW: 234.3 D
Formula: C14H10N4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 531-46-4| Matching products
KEGG ID : K08008 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H315, H319
P Phrases: P264, P270, P280, P301+310, P302+352, P305+351+338, P321, P330, P332+313, P337+313, P362+364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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