32 products were found matching "M2865-17.1"!

Microtubule-associated protein kinase kinase 1 (MEK1 or MAPKK1) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1&2/MAPK enzymes by phosphorylating, both residues within the threonine - glutamic acid - tyrosine (TEY) motif in the activation loop. MEK1&2 are also activated by...

Mitogen-activated protein kinase kinase 1 (MEK1 or MAPKK1, 43.5kD) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1&2/MAPK enzymes by phosphorylating both residues within the threonine-glutamic acid-tyrosine (TEY) motif in the activation loop. MEK1&2 are also activated by...

Microtubule-associated protein kinase kinase 1 (MEK1 or MAPKK1) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1&2/MAPK enzymes by phosphorylating, both residues within the threonine - glutamic acid - tyrosine (TEY) motif in the activation loop. MEK1&2 are also activated by...

Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000-1:10,000. Detects phosphorylated MEK1/2 in RIPA lysates from PC-12 cells that had been treated with 5u of B-Raf for 30 minutes at 30°C. Untreated and B-Raf phosphorylated PC-12 cell lysate was...

MEK (MAP Kinase Kinase) phosphorylates the MAP Kinase 1 and 2 on both threonine and tyrosine residues of the activation loop motif TEY. MEK1 and MEK2 are activated by phosphorylation of two serine residues (Ser218/222 in MEK1 and Ser222/226 in MEK2). These phosphorylation sites are substrates of the Raf family of...

MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221 (in the...

Detects endogenous levels of total MEK1 protein. A significant induction of MEK1 phosphorylation can be detected in PMA-treated NIH/3T3 cells using Phospho- MEK1 (Ser217/221) Sandwich ELISA Kit. However, the level of total MEK1 detected by this sandwich ELISA kit remains unchanged. This kit can also be used to...

MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr...

MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr...

MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and...

MEK1 is one of the MEKs that are upstream of the MAPK ERK1/2. MEK1 is a dual-specific protein kinase that phosphorylates ERK1/2 on both threonine and tyrosine residues in the sequence TEY. Phosphorylation of these residues dramatically activates ERK1/2, which then phosphorylate their downstream substrate. MEK1...

Microtubule-associated protein kinase kinase 1&2 (MEK1&2 or MAPKK1&2) are members of a tyrosine/threonine protein kinase family that activate the ERK1&2/MAPK enzymes by phosphorylating both residues within the threonine - glutamic acid - tyrosine (TEY) motif in the, activation loop. MEK1&2 are also activated by...