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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay760700-96 | 96 wells | - |
6 - 10 business days* |
291.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Lipoxygenases are members of a class of non-heme iron-containing dioxygenases that catalyze the... more
Product information "Lipoxygenase Inhibitor Screening Assay Kit"
Lipoxygenases are members of a class of non-heme iron-containing dioxygenases that catalyze the addition of molecular oxygen to fatty acids containing a cis,cis-1,4-pentadiene system to give an unsaturated fatty acid hydroperoxide. In mammals, lipoxygenases carry out the first step in the arachidonic acid cascade. 5- and 15-LOs lead to the biologically active lipoxins, whereas 5-LO leads to 5,6-epoxy-leukotrienes which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. In contrast, Nassar, et al., suggested that animal 15-LO products act as anti-inflammatory agents. This implies that the 5- and 15-LO pathways may play a role in regulating inflammation. To elucidate the role of each lipoxygenase, it is particularly important to develop inhibitors that are enzyme specific. This assay kit provides an accurate and convenient method for screening lipoxygenase inhibitors. This assay measures the hydroperoxides generated from the incubation of a lipoxygenase (5-, 12-, or 15-LO) with either arachidonic or linoleic acid.Synonyms: LO Inhibitor Screening Assay Kit. Origin: Plant/Glycine max.
Keywords: | LO Inhibitor Screening Assay Kit |
Supplier: | Cayman Chemical |
Supplier-Nr: | 760700 |
Properties
Application: | LO inhibitor screening |
Format: | Homog. |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H225, H302, H315, H319, H335, H350 |
P Phrases: | P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+310, P302+352, P303+361+353, P304+340, P305+351+338, P308+313, P312, P321, P330, P332+313, P337+313, P362+364, P370+378, P403+233, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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