24 products were found matching "324"!

L-701,324 is an NMDA receptor antagonist. It inhibits NMDA-induced currents in rat cortical neurons (Ki = 5.4 nM). L-701,324 inhibits seizures induced by N-methyl-DL-aspartate, pentylenetetrazole (PTZ, Cay-18682), or electroshock, as well as audiogenic seizures in mice (ED50s = 3.5, 2.8, 1.4, and 0.96 mg/kg,...

Heat shock proteins, HSP's or stress response proteins SRP's, are synthesized in a variety of environmental and patholphysiological stressful conditions. Many HSP's are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion....

Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. Applications: Suitable for use in Western Blot. Other applications not...

R428 is a small molecule inhibitor of Axl kinase, both in an in vitro biochemical assay and in a cell-based assay using phosphorylation of Ser473 on Akt as the readout (EC50s = 14 nM for both). It is orally bioavailable, blocks angiogenesis in corneal micropocket and tumor models, and reduces metastatic burden while...

ML-324 is a cell-permeable inhibitor of JMJD2E (KDM4DL, IC50 = 920 nM) that is inactive against lysine-specific demethylase, LSD1. It reduces the expression of immediate early genes of Herpes simplex virus (IC50 = ~10 µM) and human cytomegalovirus, blocks viral infection, and suppresses the level of viral...

Mouse polyclonal antibody raised against a full-length human ZNF324 protein. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence:...

Source:, Recombinant protein corresponding to aa2-324 from human DNAJB2, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~51.4kD, AA Sequence:...

Source:, Recombinant protein corresponding to aa51-324 from human MRPL1, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~47.3kD, AA Sequence:...

Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and...

Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. Source: Recombinant protein corresponding to aa1-324 from human TXNDC5, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~63.2kD, AA Sequence:...

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Source: Recombinant protein corresponding to aa1-324 from porcine CAPN2, fused to His-SUMO-Tag at N-terminal,...