- Search results for 715
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22 products were found matching "715"!
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Item number: Cay36890-5
R 715 is a bradykinin B1 receptor antagonist. It inhibits contractions induced by bradykinin (Cay-37408) in isolated human umbilical cords, which express bradykinin B1 receptors (pA2 = 8.49). R 715 (200, 400, and 600 µg/kg) decreases the latency to tail withdrawal in the tail-flick test in a mouse model of diabetic...
Keywords: | [Ac-Lys-[D-betaNal7,Ile8]des-Arg9]-BK, Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile-OH,... |
Application: | Bradykinin B1 receptor antagonist |
MW: | 1140.3 D |
From 377.00€
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Item number: ABD-715
Oregon Green(R) is a trademark of Life Technologies.
Keywords: | Oregon Green(R) is a trademark of Life Technologies. This product is equivalent to analog488 maleimide (715) on the AAT... |
Application: | Conjugation |
279.00€
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Item number: P6200-50.200
Prekallikrein (PK), previously known as Fletcher Factor, is a single chain glycoprotein produced in the liver. The plasma concentration of PK is 50ug/ml (550nM), approximately 75% of which circulates in complex with high molecular weight kininogen (HK) and the remainder as free PK. Plasma PK is heterogeneous in both...
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | human |
From 991.00€
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Item number: SYN-1087-M005
Soluble in DMSO or ethanol. TAK-715 is a potent specific inhibitor of the p38alpha MAP kinase with an IC(50) of 7.1nM. It is approximately 30-fold more selective for p38alpha over p38beta. It shows no inhibition of p38gamma/delta. Target: p38 , Kinase Group: CMGC , Substrate: Serine-Threonine
Keywords: | TAK715 |
Application: | p38 alpha inhibitor |
CAS | 303162-79-0 |
MW: | 399,5 D |
From 92.00€
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Item number: Cay26170-5
TAK-715 is an inhibitor of p38alpha MAPK (IC50 = 7.1 nM). It is selective for p38alpha over p38beta (IC50 = 200 nM), as well as over p38gamma/delta, JNK, ERK1, IKKbeta, MEKK1, and TAK1 (IC50 = >10 µM for all) but also inhibits casein kinase Idelta (CK1delta) and CK1epsilon. It inhibits TNF-alpha release induced by...
Keywords: | N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-benzamide |
Application: | MAPK14 / p38 alpha inhibitor |
CAS | 303162-79-0 |
MW: | 399.5 D |
From 109.00€
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Item number: DC-715-H01-010-CF
HIS Tag C-Terminus Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the...
Keywords: | CDF, IL-6, BSF-2, IFNB2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation... |
Expressed in: | Human cells |
Origin: | human |
From 187.00€
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Item number: DC-715-H02-025-CF
HIS Tag C-Terminus. Lyophilised, PBS. Carrier-free. Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated...
Keywords: | IL2, TCGF, IL-2, Aldesleukin, Interleukin-2, T-cell growth factor |
Expressed in: | Human cells |
Origin: | human |
From 187.00€
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Item number: DC-715-H16-0BU
Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651,...
Keywords: | 2 |
Expressed in: | Human cells |
Origin: | SARS-CoV-2 |
519.00€
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Item number: DC-715-H17-0BU
Protein function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as...
Keywords: | N, NC, Protein N, Nucleoprotein, Nucleocapsid protein |
Expressed in: | Human cells |
Origin: | SARS-CoV-2 |
519.00€
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Item number: DC-715-H19-0BU
Protein function: Essential counter-regulatory carboxypeptidase of the renin- angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed:27217402). Converts angiotensin I to angiotensin 1- 9, a nine-amino acid peptide with...
Keywords: | Recombinant Human Angiotensin-converting enzyme 2 (ACE2) Extracellular Domain |
Origin: | human |
519.00€
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COVID-19 Research
Item number: DC-715-H20-0BU
NCBI Accession Number: MN908947, Arg319-Phe541 with N501Y mutation. Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces...
Keywords: | VOC-202012/01 (United Kingdom) 20I/501Y.V1 Alpha RBD Variant GR/501Y.V1/20I(V1) |
Expressed in: | Human cells |
Origin: | SARS-CoV-2 |
519.00€
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COVID-19 Research
Item number: DC-715-H21-0BU
NCBI Accession Number: MN908947, Arg319-Phe541 with K417N, E484K, N501Y mutations. Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host...
Keywords: | 20C/501Y.V2 (South Africa) Beta RBD Variant GH/501Y.V2 / 20H (V2) |
Expressed in: | Human cells |
Origin: | SARS-CoV-2 |
519.00€
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