- Search results for 702
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18 products were found matching "702"!
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Item number: ABD-702
Bodi Fluor 488 amine is an excellent building block for developing fluorescent probes. Bodi Fluor 488 is the same fluorophore as BODIPY FL (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene FL). It is a popular lipophilic fluorescent dye molecule used in biology, chemistry, and materials science. BODI Fluor 488 has high...
Application: | Fluorescent probe building block |
MW: | 462.23 D |
369.00€
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Item number: H7950-20.50
Protein produced in genetically engineered yeast cells as a fusion protein with human superoxide dismutase (SOD). It covers from Asp 166 to Arg 440 (D Ala 313 to Ala 331) of the HTLV-I envelope protein (isolate ATK-1). Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot...
682.00€
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Item number: H7950-22.100
Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:100-1:1000, Western Blot: 1:100-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing...
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | human |
848.00€
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Item number: V5800.10
VX-702 is a second-generation, orally active mitogen-activated protein kinase (MAPK) p38 inhibitor. It is being tested for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases. Solubility: Soluble in DMSO. Storage and Stability: May be stored at RT for short-term only. Long-term...
CAS | 745833-23-2 |
MW: | 404.32 |
226.00€
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Item number: Cay13108-5
VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1beta, and TNF-alpha production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml,...
Keywords: | 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide |
Application: | p38 MAP kinase inhibitor |
CAS | 745833-23-2 |
MW: | 404.3 D |
From 34.00€
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Item number: LKT-V9202.25
VX-702 inhibits p38 MAPK, preventing p38 MAPK-dependent inflammatory cytokine release. VX-702 is in development to treat inflammation and cardiovascular diseases and currently shows mixed results in clinical trials as a potential treatment for rheumatoid arthritis. In vitro, VX-702 decreases platelet lesioning in...
Keywords: | VX702 |
Application: | p38 MAPK inhibitor |
CAS | 479543-46-9 |
MW: | 404.32 D |
From 90.00€
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Item number: SYN-1093-M050
Soluble in DMSO or ethanol. The kinases called p38 MAP kinases (MAPKs) are intracellular, soluble serine-threonine kinases which belong to a large family of proteins that include the extracellular regulated kinases (ERKs) and c-Jun N-terminal kinases (JNKs). So far four p38 isoforms have been identified, namely...
Keywords: | VX702 |
Application: | P38 inhibitor |
CAS | 745833-23-2 |
MW: | 404,3 D |
From 66.00€
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Item number: 702-100-002
Format - F(ab')2
Host: | Goat |
Species reactivity: | cat |
226.00€
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Item number: 702-400-002
Format - F(ab')2, affinity purified
Host: | Rabbit |
Species reactivity: | cat |
256.00€
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Item number: 702-402-002
Format - F(ab')2, affinity purified
Application: | FLISA, FC, IFM |
Host: | Rabbit |
Species reactivity: | cat |
256.00€
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Item number: 702-403-002
Format - F(ab')2, affinity purified
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | cat |
315.00€
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Item number: 702-405-002
Format - F(ab')2, affinity purified
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | cat |
336.00€
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