11 products were found matching "712-0030"!

Preservative free antibody. Antibody RA3-3A1 binds to an extracellular epitope of B220 (CD45R), the 220 kD variant of the T200, CD45 molecule present on B cells and B cell precursors. CD45R is implicated in a signaling pathway that involves motility and dendrite formation.

This product is prepared by labeling high quality goat anti-mouse IgG (H+L) with CF(R)555 dye. CF(R) dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Orange-red fluorescent CF(R)555 dye has...

The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). 2,4-DPD is a cell permeable, competitive inhibitor of HIF-PH. 2,4-DPD inhibits the hydroxylation of...

Annexins are a family of proteins that bind to phospholipid membranes in the presence of calcium. Annexin V is a valuable tool for studying cell apoptosis. It is used as a probe to detect cells which have expressed phosphatidylserine on the cell surface, a feature found in apoptosis as well as other forms of cell...

Nerve Terminal Staining Kits contain Biotium's nerve terminal dyes and background reducing agents for washing away or quenching extracellular dye fluorescence. Kits are available with SynaptoGreen(TM) C4 (equivalent to FM(R)1-43), the fixable green nerve terminal dye AM1-43, or SynaptoRed(TM) C2 (equivalent to...

TP-472 is an inhibitor of bromodomain BRD9 (Kd = 33 nM, EC50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (Kd = 340 nM in an isothermal titration calorimetry (ITC) assay). See the Structural Genomic...

BirA, also known as biotin ligase. GenBank Accession No. AP012306 (3602298-3603260), amino acids 2 ? 321 (end) with His-FLAG tag, MW = 37.1 kDa, expressed in an E. coli cell expression system.

Isolated from Micromonospora rhodorangea. Antibiotic. Cytotoxic to prokaryotic and eukaryotic cells by inhibiting the protein synthesis. Apoptosis inducer. Widely employed in the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II. Antiviral. Assay:...

Human CD46-BC, also known as membrane co-factor protein, Genbank Accession No. BC_030594, a.a. 35-328 with C-terminal His-tag, expressed in a HEK293 cell expression system. MW = 36.6 kDa (precursor), 34.2 kDa (mature). Note: this protein is expressed with a 34 amino acid signal sequence that is cleaved after...

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue...

Corey lactone aldehyde benzoate is a versatile, chiral intermediate used in the preparation of prostaglandins and prostaglandin analogs.Formal Name: [3aR-(3aalpha,4alpha,5beta,6aalpha)]5-(benzoyloxy)hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde. CAS Number: 39746-01-5. Molecular Formula: C15H14O5. Formula...