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ON-01910 (sodium salt)
ON-01910 (sodium salt)

Item number: Cay15553-1

ON-01910 is a potent, non-ATP-competitive inhibitor of polo-like kinase 1 (Plk1, IC50 = 9 nM), a serine/threonine protein kinase involved in the regulation of cell cycling. It induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) and blocks the growth of multidrug resistant cancer cell lines....
Keywords: Rigosertib, N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-glycine, monosodium salt
Application: Plk1 inhibitor
CAS 1225497-78-8
MW: 473.5 D
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