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Item number: Cay15428-100

Lamotrigine is an anticonvulsant. It inhibits voltage-gated sodium channels (Nav) in HEK293 cells expressing recombinant human Nav1.2, Nav1.5, or Nav1.8 (IC50s = 10, 62, and 96 µM, respectively), as well as high voltage-activated calcium currents in isolated rat cortical neurons (IC50 = 12.3 µM), an effect that can...

Keywords:	BW 430C, Epilepax, Lamictal, LTG, 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Application:	Voltage-gated sodium channel inhibitor
CAS	84057-84-1
MW:	256.1 D

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