2 products were found matching "Cay70715"!

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LY255283
LY255283

Item number: Cay70715-10

Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4) have been potential drug development targets for several years. The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100...
Keywords: 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]-ethanone
Application: BTL2 receptor antagonist
CAS 117690-79-6
MW: 360.5 D
From 34.00€ *
Review
LY171883
LY171883

Item number: Cay70710-5

LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor. Dissociation constants (KB) for LY171883 on guinea pig ileum and parenchyma are 0.07 and 0.34 µM, respectively. LY171883 is an inhibitor of phosphodiesterase obtained from human polymorphonuclear leukocytes (IC50 of 22.6 µM)...
Keywords: 1-[2-hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)butoxy]phenyl]-ethanone
Application: CysLTR1 antagonist
CAS 88107-10-2
MW: 318.4 D
From 54.00€ *
Review