7 products were found matching "Cay10245-25"!

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NADP+ (hydrate)
NADP+ (hydrate)

Item number: Cay21045-250

NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate (NADPH, Cay-9000743). It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the...
Keywords: Coenzyme II, Nicotinamide adenine dinucleotide phosphate, TPN, beta-NADP, adenosine 5'-(trihydrogen diphosphate),...
Application: Cofactor
MW: 743.4 D
From 46.00€ *
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L-threo-PPMP (hydrochloride)
L-threo-PPMP (hydrochloride)

Item number: Cay24525-10

L-threo-PPMP is an inhibitor of glucosylceramide synthetase and isomer of D-threo-PPMP (Cay-22677). It inhibits the growth of MCF-7, MDA-MB-468, and SK-BR-3 breast cancer cells (ED50s = 4, 7, and 6 µM, respectively) through damage of cell organelle membranes, increasing ceramide concentration, and induction of...
Keywords: L-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol,...
Application: Glucosylceramide synthase inhibitor
MW: 511.2 D
530.00€ *
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GPR55 Blocking Peptide
GPR55 Blocking Peptide

Item number: Cay10225-1

To be used in conjunction with Cayman's GPR55 Polyclonal Antibody (Cay-10224) to block protein-antibody complex formation during immunochemical analysis of GPR55 for Western blot (WB).Synonyms: G Protein-Coupled Receptor 55, LIP1, Lysophosphatidylinositol Receptor 1. Formulation: (Request formulation change), 200 µg...
Keywords: G Protein-Coupled Receptor 55, LIP1, Lysophosphatidylinositol Receptor 1
Application: ICC, IF, IHC, WB
177.00€ *
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Columbin
Columbin

Item number: Cay24105-25

Columbin is a diterpenoid furanolactone isolated from J. columba, A. albida, and T. bakis that has diverse biological activities. It inhibits the growth of T. brucei in vitro and induces complete parasite clearance in T. brucei-infected mice when administered at a dose of 25 mg/kg per day for three days. Columbin...
Keywords: 9-(3-furanyl)-1R,4R,4aR,5,6,6aR,9S,10,10aS,10bS-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']di...
Application: Diterpenoid
CAS 546-97-4
MW: 358.4 D
From 60.00€ *
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PK 11195
PK 11195

Item number: Cay10525-10

Benzodiazepines bind two types of receptors, the central gamma-aminobutyric acid A receptor and the peripheral translocator protein (TSPO). PK11195 binds the peripheral benzodiazepine receptor, TSPO, with selectivity and high affinity (Ki = 3.1 nM in cerebellum, 4.1 nM in spinal cord). PK11195, which lacks the...
Keywords: RP 52028, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Application: TSPO blocking, TSPO detection
CAS 85532-75-8
MW: 352.9 D
From 109.00€ *
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XL147 analog
XL147 analog

Item number: Cay20245-25

XL147 analog is an analog of XL147 (Cay-18011).Formal Name: N-[3-(2,1,3-benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-benzenesulfonamide. CAS Number: 956958-53-5. Molecular Formula: C21H16N6O2S2. Formula Weight: 448.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility:...
Keywords: Pilaralisib analog, SAR245408 analog, N-[3-(2,1,3-benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-benzenesulfonamide
Application: XL147 derivative
CAS 956958-53-5
MW: 448.5 D
From 43.00€ *
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NEW
PF-05190457
PF-05190457

Item number: Cay40142-25

PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Keywords: 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi...
Application: GHS-R inverse agonist
CAS 1334782-79-4
MW: 512.7 D
From 47.00€ *
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