Stearidonic Acid (18:4omega-3) is a rare polyunsaturated fatty acid of the omega-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. It is present in certain natural oils such as echium and black currant seed, and to the extent that these oils are incorporated into...

Fatty acid binding protein 1 (FABP1) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids. FABP1 is composed of ten antiparallel beta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids. Expression of...

Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-2 is a nutlin-3 analog in which trifluoromethyl groups have been substituted for chlorine on the 2 phenyl rings. At high concentrations, caylin-2 inhibits the growth of HCT116...

The Atherosclerosis Product Pack contains our human SOAT-1/ACAT-1 polyclonal antibody and blocking peptide. Targeting human amino acids 6-23 of the sterol O-acyltransferase 1/acyl-Coenzyme A: cholesterol acyl transferase-1, these reagents can be used for western blot analysis. Also included are several oxidized...