- Search results for Cay10011562
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5 products were found matching "Cay10011562"!
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Item number: Cay10011565-25
Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
Keywords: | N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony... |
Application: | EP4 receptor antagonist |
CAS | 147776-06-5 |
MW: | 654.7 D |
From 50.00€
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Item number: Cay10011561-25
SC-51089 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP1 (Ki = 1.332 µM). It is selective for EP1 over EP2, EP3, and EP4 (Kis = >100, 17.5, and >100 µM, respectively), as well as the PGD2 receptor DP, PGF2alpha receptor FP, PGI2 receptor IP, and thromboxane A2 receptor TP (Kis = >100, 61.13,...
Keywords: | CID132748, 8-chloro-2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,... |
Application: | EP1 antagonist |
CAS | 146033-02-5 |
MW: | 459.3 D |
From 31.00€
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Item number: Cay10011256-5
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis and its activity is increased in many proliferating tissues and tumors, which lends promise as an anti-cancer drug target. CAY10577 inhibits CK2 with an...
Keywords: | 7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
Application: | CK2 inhibitor |
CAS | 300675-28-9 |
MW: | 258.1 D |
From 24.00€
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Item number: Cay10012562-1
Stearoyl-CoA desaturase (SCD) catalyzes the committed step of the conversion of saturated, long-chain fatty acids to monounsaturated fatty acids. The SCD1 gene is thought to play a key role in lipid homeostasis and body weight regulation. Thus, modulating SCD1 activity pharmacologically may be a useful tool for...
Keywords: | 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)-pyridazine |
Application: | SCD inhibitor |
CAS | 944808-88-2 |
MW: | 389.8 D |
From 106.00€
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Item number: Cay10010562-1
Prostaglandin F2alpha (PGF2alpha) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2alpha are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor PGF2alpha is a metabolically stable form of PGF2alpha containing a 16-phenoxy group at the...
Keywords: | 16-phenoxy tetranor PGF2alpha methyl amide,... |
Application: | Bioactive Lipid Assays |
MW: | 403.5 D |
From 74.00€
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