6 products were found matching "Cay10011565"!
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L-161,982
Item number: Cay10011565-1
Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
| Keywords: | N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony... |
| Application: | EP4 receptor antagonist |
| CAS | 147776-06-5 |
| MW: | 654.7 D |
From 50.00€
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Ramatroban
Item number: Cay10156-5
Ramatroban is a dual TP and DP2/CRTH2 receptor antagonist (Kis = 4.5 and 4.3 nM for the human receptors, respectively). It is selective for these receptors over the prostaglandin E2 (PGE2) receptor subtypes EP1 and EP2, as well as the FP and IP receptors, at 1 µM. Ramatroban inhibits contractions induced by U-46619...
| Keywords: | Ramatroban, 3R-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid |
| Application: | DP2 receptor antagonist |
| CAS | 116649-85-5 |
| MW: | 416.5 D |
From 43.00€
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SC-51089
Item number: Cay10011561-5
SC-51089 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP1 (Ki = 1.332 µM). It is selective for EP1 over EP2, EP3, and EP4 (Kis = >100, 17.5, and >100 µM, respectively), as well as the PGD2 receptor DP, PGF2alpha receptor FP, PGI2 receptor IP, and thromboxane A2 receptor TP (Kis = >100, 61.13,...
| Keywords: | CID132748, 8-chloro-2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,... |
| Application: | EP1 antagonist |
| CAS | 146033-02-5 |
| MW: | 459.3 D |
From 31.00€
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CAY10577
Item number: Cay10011256-5
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis and its activity is increased in many proliferating tissues and tumors, which lends promise as an anti-cancer drug target. CAY10577 inhibits CK2 with an...
| Keywords: | 7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Application: | CK2 inhibitor |
| CAS | 300675-28-9 |
| MW: | 258.1 D |
From 24.00€
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3-O-methyl-N-acetyl-D-Glucosamine
Item number: Cay10011056-5
3-O-methyl-N-acetyl-D-Glucosamine (3-O-methyl-GlcNAc) is a competitive inhibitor of N-acetylglucosamine kinase and a non-competitive inhibitor of N-acetylmannosamine kinase (Kis = 17 and 80 µM in rat liver, respectively, in vitro).Formal Name: 2-(acetylamino)-2-deoxy-3-O-methyl-D-glucose. CAS Number: 94825-74-8....
| Keywords: | 3-O-methyl-GlcNAc, 2-(acetylamino)-2-deoxy-3-O-methyl-D-glucose |
| Application: | N-acetylglucosamine kinase inhibitor, N-acetylmannosamine kinase inhibitor |
| CAS | 94825-74-8 |
| MW: | 235.2 D |
From 66.00€
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Glycerophospho-N-Palmitoyl Ethanolamine
Item number: Cay10011356-5
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. For example, arachidonoyl ethanolamide (AEA) is an endogenous neurotransmitter that evokes cellular responses by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). The...
| Keywords: | GP-NAE, GP-NPEA, mono(2,3-dihydroxypropyl)-mono[2-[(1-oxohexadecyl)amino]ethyl]ester phosphoric acid |
| Application: | Metabolic studies |
| CAS | 100575-09-5 |
| MW: | 453.6 D |
From 113.00€
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