Ki16425

Ki16425
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10012659-1 1 mg -

6 - 10 business days*

50.00€
Cay10012659-5 5 mg -

6 - 10 business days*

131.00€
Cay10012659-10 10 mg -

6 - 10 business days*

191.00€
Cay10012659-100 100 mg -

6 - 10 business days*

1,180.00€
 
Lysophosphatidic acid (LPA) is a bioactive lipid mediator that signals through five distinct G... more
Product information "Ki16425"
Lysophosphatidic acid (LPA) is a bioactive lipid mediator that signals through five distinct G protein-coupled receptors (LPA1-5). Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 µM for the human LPA1, LPA2, and LPA3 receptors, respectively, as determined by measuring inositol phosphate production in RH7777-transfected cells. Ki1642, at 10 µM, significantly blocks the response of a variety of cancer cell lines to LPA-induced cell migration.Formal Name: 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazoly]phenyl]methyl]thio]-propanoic acid. CAS Number: 355025-24-0. Molecular Formula: C23H23ClN2O5S. Formula Weight: 475.0. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 12 mg/ml, DMSO: 10 mg/ml, DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml, Ethanol: 10 mg/ml, Methyl Acetate: 20 mg/ml. lambdamax: 276 nm. SMILES: OC(=O)CCSCc1ccc(cc1)c1onc(C)c1NC(=O)OC(C)c1ccccc1Cl. InChi Code: InChI=1S/C23H23ClN2O5S/c1-14-21(25-23(29)30-15(2)18-5-3-4-6-19(18)24)22(31-26-14)17-9-7-16(8-10-17)13-32-12-11-20(27)28/h3-10,15H,11-13H2,1-2H3,(H,25,29)(H,27,28). InChi Key: LLIFMNUXGDHTRO-UHFFFAOYSA-N.
Keywords: 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazoly]phenyl]methyl]thio]-propanoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10012659

Properties

Application: LPA receptor antagonist
MW: 475 D
Formula: C23H23ClN2O5S
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 355025-24-0| Matching products
KEGG ID : K04289 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Ki16425"
Write a review
or to review a product.
Viewed