5 products were found matching "Cay11208-250"!

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KRN 7000
KRN 7000

Item number: Cay11208-500

KRN 7000 is a potent synthetic alpha-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases,...
Keywords: N-[(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]-hexacosanamide
Application: Synthetic alpha-galactosylceramide, Bioassays
CAS 158021-47-7
MW: 858.3 D
From 265.00€ *
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PF-8380
PF-8380

Item number: Cay12018-25

Autotaxin converts lysophosphatidylcholine to lysophosphatidic acid (LPA), which can mediate changes in cell proliferation, angiogenesis, and cytokine secretion. PF-8380 is a potent inhibitor of autotaxin (IC50 = 2.8 nM in an enzyme assay), the enzyme that converts lysophosphatidylcholine to lysophosphatidic acid...
Keywords: 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-(3,5-dichlorophenyl)methyl ester-1-piperazinecarboxylic acid
Application: Autotaxin Inhibitor
CAS 1144035-53-9
MW: 478.3 D
From 65.00€ *
Review
SANT-2
SANT-2

Item number: Cay21208-50

SANT-2 is a Smoothened (Smo) receptor antagonist. It binds to the Smo receptor (Kd = 12 nM) and inhibits binding of the Smo receptor agonist SAG-1.3 (SAG, Cay-11914) and antagonist cyclopamine (Cay-11321) (Kis = 7.8 and 8.4 nM, respectively). SANT-2 inhibits hedgehog signaling induced by an N-terminal fragment of...
Keywords: N-[3-(1H-benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxy-benzamide
Application: Hh signaling Antagonist
CAS 329196-48-7
MW: 480 D
From 98.00€ *
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R-(-)-Mandelic Acid
R-(-)-Mandelic Acid

Item number: Cay10007128-250

R-(-)-Mandelic Acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: alphaR-hydroxy-benzeneacetic acid. CAS Number: 611-71-2. Synonyms: D-(-)-Mandelic Acid. Molecular Formula: C8H8O3. Formula Weight: 152.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid....
Keywords: D-(-)-Mandelic Acid, alphaR-hydroxy-benzeneacetic acid
Application: Synthetic intermediate, Pharmaceutical synthesis
CAS 611-71-2
MW: 152.2 D
From 82.00€ *
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Oxyresveratrol
Oxyresveratrol

Item number: Cay12028-50

Resveratrol is a potent phenolic antioxidant found in the skin of grapes and red wine that has anti-proliferative, anti-inflammatory, and cardioprotective properties. Oxyresveratrol is a naturally occurring analog of resveratrol found in mulberry wood. It effectively scavenges H2O2, NO (IC50 = 45.3 µM), and the...
Keywords: trans-2',3,4',5-Tetramethoxystilbene, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,3-benzenediol
Application: Antioxidant, Chemopreventive
CAS 29700-22-9
MW: 244.2 D
From 125.00€ *
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