- Search results for Cay14497
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3 products were found matching "Cay14497"!
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Item number: Cay14497-10
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: | N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide |
Application: | FAAH inhibitor |
CAS | 681136-29-8 |
MW: | 365.5 D |
From 98.00€
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Item number: Cay14997-10
Phenformin is an antihyperglycemic biguanide. It reduces blood glucose levels in a mouse model of diabetes induced by alloxan (Cay-9002196) when administered at a dose of 100 mg/kg. Phenformin (250 mg/kg) induces lactic acidosis in diabetic dogs. It also inhibits tumor growth of MCF-7 and MDA-MB-231 breast cancer...
Keywords: | N-(2-phenylethyl)-imidodicarbonimidic diamide, monohydrochloride |
Application: | AMPK activator |
CAS | 834-28-6 |
MW: | 241.7 D |
From 54.00€
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Item number: Cay11497-5
Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion,...
Keywords: | AZD 0530,... |
Application: | c-Src / Abl inhibitor |
CAS | 379231-04-6 |
MW: | 542 D |
From 42.00€
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