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| ART-NR | PRODUKT | HERSTELLER | MENGE | PREIS | |
| Cay11237-50 |
JMJD2E-Strep tagged (human recombinant) |
Cayman |
50 µg |
210 €
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Demethylation assays  Recombinant N-terminal Strep II-tagged protein expressed in E. coli. Mr: 40.8 kDa. Methylation of lysine residues in core histones plays a critical role in regulating gene expression. Jumonji domain containing 2E (JMJD2E) catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residues 9 and 27 (me 2/3), leading to transcriptional repression and activation, respectively. Like other JmjC protein hydroxylase family members, JMJD2E is an alpha-ketoglutate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can result in displacement of the catalytic iron and decreased activity, therefore this this Strep-tagged protein is purified by affinity chromatography using Strep-Tactin coated resin. Because of their implication in cancer cell growth, jumonji C domain-containing histone demethylase inhibitors may have the capacity to be anticancer agents. MW: 40 kD Purity: >75% UniProt ID: B2RXH2  Loading ... - Geninformationen GeneID 390245 Weitere Produkte für dieses Protein:Antibodies Enzymes & Proteins
ELISA and Assay Kits Schlagworte: EC=1.14.11.-, KDM4D-like, JMJD2E, KDM4DL, Lysine-specific demethylase 4D-like, KDM4D-like protein KDM4DL, EC=1.14.11.-, KDM4D-like protein, Lysine-specific demethylase 4D-like | |||||
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Datenbank vom 21.05.2013, 15:40 Uhr Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer |
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