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L-798,106
L-798,106

Item number: Cay11129-50

Prostaglandin E2 (Cay-14010) exerts its effects through four separate G-protein coupled receptors (EP1, EP2, EP3, and EP4). L-798,106 is a highly selective EP3 receptor antagonist with Ki values of 0.3, 916, >5,000, and >5,000 nM at EP3, EP4, EP1, and EP2, respectively. At 0.2 µM, it blocks the EP3 agonist activity...
Keywords: CM 9, GW 671021, (2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide
Application: EP3 receptor antagonist
CAS 244101-02-8
MW: 536.4 D
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