- Search results for Cay14451
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10 products were found matching "Cay14451"!
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Item number: Cay11445-1
Tunicamycin mixture is a mixture of tunicamycins with variable trans-2,3-unsaturated branched chain fatty acid (BFCA) chain lengths. Tunicamycins are anti-microbial agents that are active against Gram-positive bacteria, fungi, and viruses. They inhibit the N-acetylhexosamine (HexNAc) phosphotransferase family of...
Application: | N-glycosylation inhibitor |
CAS | 11089-65-9 |
MW: | 845 D |
From 43.00€
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Item number: Cay14445-1
Ketanserin is a potent antagonist of the serotonin receptor 5-HT2A (Ki = 3.16 nM) that has hypertensive effects in vivo. RH-34 is a derivative of ketanserin in which the 4-(p-fluorobenzoyl)piperidine group has been replaced with an N-(2-methoxybenzyl) moiety. In phenethylamines, which are 5-HT2A agonists, this...
Keywords: | 3-[2-[[(2-methoxyphenyl)methyl]amino]ethyl]-2,4(1H,3H)-quinazolinedione |
Application: | Analytical reference standard, ketanserin analog |
CAS | 1028307-48-3 |
MW: | 325.4 D |
From 84.00€
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Item number: Cay14555-1
PB-22 (Cay-14096) is a synthetic cannabinoid that is structurally analogous to the potent aminoalkylindoles like JWH 018 (Cay-10900). It differs from JWH 018 by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. PB-22 5-hydroxyisoquinoline isomer is a structural isomer of PB-22. The physiological...
Keywords: | 1-pentyl-1H-indole-3-carboxylic acid, 5-isoquinolinyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog, PB-22 structural isomer |
CAS | 2365471-14-1 |
MW: | 358.4 D |
From 109.00€
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Item number: Cay11451-100
Physical exertion and exercise are the primary defenses against obesity, insulin resistance, and diabetes. The transcriptional co-activator peroxisome proliferator-activated receptor C coactivator 1alpha (PGC-1alpha), regulates mitochondrial biogenesis and function. Expression of the membrane protein Fibronectin...
Keywords: | FNDC5, FRCP2, Irisin, Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2 |
Application: | Bioassays |
Expressed in: | E.coli |
Origin: | human |
CAS | 9037-90-5 |
MW: | 12.4 kD |
642.00€
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Item number: Cay14511-5
5-fluoro PB-22 (Cay-14095) is a synthetic cannabinoid that is an analog of potent 5-fluoropentyl JWH-type cannabimimetics. 5-fluoro PB-22 3-hydroxyquinoline isomer differs from 5-fluoro PB-22 by having the ester linkage inserted at the three, rather than at the eight, position of the quinoline moiety. The...
Keywords: | 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid, 3-quinolinyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 2365471-26-5 |
MW: | 376.4 D |
From 109.00€
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Item number: Cay14551-5
5-fluoro PB-22 (Cay-14095) is a synthetic cannabinoid that is an analog of potent 5-fluoropentyl JWH-type cannabimimetics. 5-fluoro PB-22 6-hydroxyisoquinoline isomer differs from 5-fluoro PB-22 by having the quinoline group replaced with an isoquinoline group attached at its six position. The physiological and...
Keywords: | 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid, 6-isoquinolinyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 2365471-44-7 |
MW: | 376.4 D |
From 109.00€
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Item number: Cay14459-1
During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 µM), as well as related caspases. Caspase activity can be quantified by...
Keywords: | Caspase-3 Substrate (Fluorogenic), N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-Trifluoromethylcoumarin,... |
Application: | Caspase activity studies |
CAS | 201608-14-2 |
MW: | 729.6 D |
From 68.00€
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Item number: Cay14450-1
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can...
Keywords: | PARP Inhibitor III, 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone |
Application: | PARP inhibitor |
CAS | 129075-73-6 |
MW: | 302.4 D |
From 76.00€
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Item number: Cay14452-1
Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane. Phloretin also blocks the sodium/D-glucose...
Keywords: | NSC 407292, RJC 02792, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone |
Application: | Monocarboxylate transporter inhibitor |
CAS | 60-82-2 |
MW: | 274.3 D |
From 56.00€
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Item number: Cay14435-1
Asperlactone is a polyketide synthase-derived polyketide that has been found in A. westerdijkiae and has anti-inflammatory activity. It inhibits superoxide anion release induced by N-formyl-Met-Leu-Phe (fMLP, Cay-21495) in isolated human neutrophils when used at a concentration of 10 µM.Formal Name:...
Keywords: | 5R-[(1S)-1-hydroxyethyl]-3-[(2S,3S)-3-methyl-2-oxiranyl]-2(5H)-furanone |
Application: | Bioassays |
CAS | 76375-62-7 |
MW: | 184.2 D |
From 125.00€
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