Interleukin-8, human recombinant (rHuIL-8) (His)

Interleukin-8, human recombinant (rHuIL-8) (His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HR-20008-C010 10 µg - -

3 - 9 business days*

187.00€
CHI-HR-20008-C050 50 µg - -

3 - 9 business days*

561.00€
 
Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor... more
Product information "Interleukin-8, human recombinant (rHuIL-8) (His)"
Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes and various tumor cell lines, produce IL-8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS and viruses. IL-8 has a wide range of other proinflammatory effects. It is a potent chemoattractant for neutrophils and causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a co-mitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro.
Keywords: Interleukin-8, CXCL8, C-X-C Motif Chemokine 8, Emoctakin, GCP-1, LAI, MDNCF, MONAP, NAP-1, NCF, TCF
Supplier: Chimerigen Laboratories
Supplier-Nr: HR-20008

Properties

Application: Bioassays
Conjugate: No
Host: E.coli
Species reactivity: human
Purity: >95%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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