7 products were found matching "94906.2"!

AZD 9496 is a potent and selective estrogen receptor downregulator (SERD) with an IC50 value of 0.138 nM for estrogen receptor alpha (ERalpha) downregulation. It is selective for ERalpha compared to other nuclear hormone receptors with IC50 values of 0.0008, 0.54, 9.2, and 30 µM for ERalpha, progesterone receptor...

Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril (3 mg/kg) reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril (10-200...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Controls phosphorylation and...

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's...

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's...

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's...