Interleukin 1 (IL-1) is a name for a family of proteins which includes IL-1alpha, IL-1beta, ILra (Interleukin receptor antagonist) and IL-18. IL-1beta is synthesized as 269 amino acid pro-cytokine that is enzymatically cleaved by IL-1beta-converting enzyme (ICE) into the active 154 amino acid, 17 kDa peptide mature...

Interleukin-1 (IL-1) is a name for a family of proteins which include IL-alpha, IL-1beta, ILra (interleukin receptor antagonist), and IL-18. IL-1alpha is synthesized as a 33 kDa (271 amino acid) pro-cytokine that is enzymatically cleaved by calpain into the active 159 amino acid, 17 kDa peptide. IL-1alpha is...

Imidazole propionate is a metabolite of histidine. It is formed from histidine via a urocanate intermediate in gut microbiota by urocanate reductase (urdA). Imidazole propionate (100 µM) decreases protein levels of insulin receptor substrate 1 (IRS-1), IRS-2, and phosphorylated Akt and increases levels of the mTORC1...

Tubercidin is a nucleoside analog that has been found in S. tubercidicus and has diverse biological activities. It is active against S. faecalis (IC50 = 0.02 µM) and cytotoxic to P388 murine leukemia and A549 human lung adenocarcinoma cells (IC50s = 0.008 and 0.019 µg/ml, respectively). Tubercidin reduces infection...

Cayman's IL-6 (mouse) ELISA Kit is an immunometric (i.e., sandwich) ELISA that permits IL-6 measurements within the range of 23.4-1,500 pg/ml, with an LLOQ of approximately 23.4 pg/ml.Synonyms: IL-6 (mouse) EIA Kit. Assay Range: 23.4-1,500 pg/ml. Cross Reactivity: (Mouse Interleukin-6) 100%, (Human Interleukin-6)...