Interleukin-36 gamma (IL-36gamma), (mouse, rec.), untagged

Interleukin-36 gamma (IL-36gamma), (mouse, rec.), untagged
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-40B-0100-C010 10 µg -

3 - 9 business days*

10 %
215.00€
193.50€
 
IL-36gamma (mouse) (aa 13-183) is untagged. Induces secretion of IL-6 in BMDCs. IL-36alpha... more
Product information "Interleukin-36 gamma (IL-36gamma), (mouse, rec.), untagged"
IL-36gamma (mouse) (aa 13-183) is untagged. Induces secretion of IL-6 in BMDCs. IL-36alpha (IL-1F6), IL-36beta(IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
Keywords: Il1f9, Il36g, IL-1F9, Interleukin-36 gamma, Interleukin-1 family member 9
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0100

Properties

Application: IL-6 secretion induction
Conjugate: No
Host: E.coli
Species reactivity: mouse
MW: 17 kD
Purity: >95%

Database Information

UniProt ID : Q8R460 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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