Interleukin-22, PEGylated, mouse recombinant (rmIL-22-PEG)

Interleukin-22, PEGylated, mouse recombinant (rmIL-22-PEG)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97317.2 2 µg - -

3 - 10 business days*

94.00€
97317.10 10 µg - -

3 - 10 business days*

208.00€
97317.1 1 mg - -

3 - 10 business days*

10,816.00€
 
Cytokine that contributes to the inflammatory response in vivo. (www.uniprot.org) PEGylated... more
Product information "Interleukin-22, PEGylated, mouse recombinant (rmIL-22-PEG)"
Cytokine that contributes to the inflammatory response in vivo. (www.uniprot.org) PEGylated Interleukin-22 Mouse Recombinant produced in E.coli is a single, non-glycosylated homodimeric polypeptide chain containing 147 amino acids and an aditional Ala amino acid at N-terminus having a molecular mass of 36 kDa as determioned by mass spectometry. However due to enlarged hydrodymanic volume it runs on the SDS-PAGE as a 50 kDa protein and in gel-filtration on Superdex 200 as over 200 kDa protein. The Murine IL-22 is Mono-PEGylated (with 20 kDa PEG) purified by proprietary chromatographic techniques. Interleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acids signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with human IL-22 and IL-10, respectively. IL-22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs.
Keywords: IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23
Supplier: Biomol GmbH
Supplier-Nr: 97317

Properties

Application: Cell culture
Conjugate: No
Host: E.coli
Species reactivity: mouse
Purity: >98%
Format: Purified

Database Information

KEGG ID : K05445 | Matching products
UniProt ID : Q9JJY9 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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