Carotenoid derivative extracted from marigold, used as an antioxidant, and can prevent many diseases, including cancer. It can also used as coloring agent in many kinds of foods, cosmetics, tobacco and medicine. Synonyms: (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol, (3R,3'R,6'R)-Lutein, (all-E)-Lutein,...

RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to act as a...

CL 316,243 is a beta3-adrenoceptor agonist (EC50 = 3 nM) that is >10,000-fold selective over beta1 and beta2. It causes a rapid decrease in blood glucose level in mice and has been used to study the induction of brown adipocytes and to increase thermogenesis in a mouse model of dietary obesity.Formal Name:...

Sertraline is a selective serotonin reuptake inhibitor (SSRI). It inhibits monoamine uptake by the serotonin transporter (SERT) with an IC50 value of 70 nM. It is selective for SERT over the norepinephrine and dopamine transporters (IC50s = 520 and 720 nM, respectively). Sertraline (3.2-56 mg/kg, s.c.) reduces...