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Interleukin-​1beta (human) EIA Kit
Ligands , Mediators human
Erklärungen der Abkürzungen ansehen.
solid phase Photometr. Immunological Lysates, Fluids ELISAErklärungen der Abkürzungen ansehen. Cayman
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Cay583311-​96 96 wells

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421 €In Warenkorb aufnehmen

Interleukin 1 (IL-​1) is a name for a family of proteins which includes IL-​1alpha, IL-​1beta, ILra (Interleukin receptor antagonist) and IL-​18. IL-​1beta is synthesized as 269 amino acid pro-​cytokine that is enzymatically cleaved by IL-​1beta-​converting enzyme (ICE) into the active 154 amino acid, 17 kDa peptide mature peptide. IL-​1beta is produced by many cell types including macrophages, monocytes, astrocytes, endothelial cells, smooth muscle cells, keratinocytes, adipocytes, T cells, and eosinophils. Although IL-​1alpha and IL-​1beta exhibit only 26% amino acid identity, they bind to the same cell-​surface receptors, IL-​1 RI and IL-​1 RII, present on a variety of cell types involved in immune or inflammatory responses. Normal production of IL-​1 is critical for mediating host responses to infection and injury. Disease states in which IL-​1 actively participates include inflammatory diseases, such as arthritis, inflammatory bowel disease, and shock, as well as arteriosclerosis, allergic disease, and some types of cancer.

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Manual
Kat #:
Cay583311-96
Menge:
96 wells

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Preis:
421 €

UniProt ID: P01584 (Protein knowledgebase)

Schlagworte:
IL1B, IL1F2, IL-​1 beta, Catabolin, Interleukin-​1 beta
Image Art 583311 Cayman Interleukin-​1beta (human) EIA Kit

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