Interleukin 1 (IL-1) is a name for a family of proteins which includes IL-1alpha, IL-1beta, ILra (Interleukin receptor antagonist) and IL-18. IL-1beta is synthesized as 269 amino acid pro-cytokine that is enzymatically cleaved by IL-1beta-converting enzyme (ICE) into the active 154 amino acid, 17 kDa peptide mature peptide. IL-1beta is produced by many cell types including macrophages, monocytes, astrocytes, endothelial cells, smooth muscle cells, keratinocytes, adipocytes, T cells, and eosinophils. Although IL-1alpha and IL-1beta exhibit only 26% amino acid identity, they bind to the same cell-surface receptors, IL-1 RI and IL-1 RII, present on a variety of cell types involved in immune or inflammatory responses. Normal production of IL-1 is critical for mediating host responses to infection and injury. Disease states in which IL-1 actively participates include inflammatory diseases, such as arthritis, inflammatory bowel disease, and shock, as well as arteriosclerosis, allergic disease, and some types of cancer.
Datenblatt ansehen
Manual
Kat #: Cay583311-96
Menge: 96 wellsBuy Bulk
Preis: 421 €
UniProt ID: P01584 (Protein knowledgebase)
Schlagworte:
IL1B, IL1F2, IL-1 beta, Catabolin, Interleukin-1 beta
 Loading ...
Relevant Pathways:
zurück
| Weitere Produkte für dieses Protein:Antibodies
- Anti-IL-1 beta, Kat #: WA-AJ1391a
- Anti-IL-1 beta (C-term), Kat #: WA-AJ1391b
- Anti-IL-1beta, clone IMG43N1F9, Kat #: IMG-6827A
- Anti-IL-1beta, clone IMG43N1G6, Kat #: IMG-6826A
- Anti-IL-1beta, clone IMG43N3D8, Kat #: IMG-6830A
- Anti-IL-1beta, clone IMG43N4C4, Kat #: IMG-6823A
- Anti-IL-1beta, clone IMG43N8F6, Kat #: IMG-6828A
- Anti-IL1B (Center), Kat #: WA-AP8531c
- Anti-IL1B (Center) (Ascites), Kat #: WA-AM2121a
- Anti-IL1B (monoclonal) (M01), Kat #: WA-AT2509a
- more
siRNA
Plasmids/Vectors
Chemicals & More
ELISA and Assay Kits
Primers
Cytokines
- IL-1beta (human) (rec.) (His), Kat #: CHI-HR-20001B-C010
- IL-1beta (human) (rec.) (His), Kat #: CHI-HR-20001B-C050
- IL-1beta (human, rec.) (untagged), Kat #: AG-40B-0023-C010
- IL-1beta (human, rec.) (untagged) (MultiPack, 3 x 10µg), Kat #: AG-40B-0023-3010
- IL-1beta (mouse, rec.) (untagged), Kat #: AG-40B-0086-C010
- IL-1beta (mouse, rec.) (untagged) (3 x 10 µg), Kat #: AG-40B-0086-3010
- Interleukin-1 beta (IL-1 beta), human recombinant (HumaXpress), Kat #: HZ-1165
- Interleukin-1 beta (IL-1 beta), human recombinant (HumaXpress), Kat #: HZ-1166
- Interleukin-1 beta (IL-1 beta), human recombinant (HumaXpress), Kat #: HZ-1164
- Interleukin-1 beta, His Tag, human recombinant (rHuIL-1-beta-His), Kat #: 95012.5
- more
Peptides
Products for: IL1B - interleukin 1 beta
|
Warenkorb
