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The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17, IL-17B through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a...

Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleiotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R), which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution and has been...

Interleukin 17C (IL-17C) is a disulfide-linked dimer belonging to the IL-17 family. IL-17 family proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Applications: Suitable for use in ELISA and Flow Cytometry. Other applications not...

Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleiotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R), which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution and has been...

IL-17 R, is a widely expressed 120kD glycosylated type I transmembrane protein that plays a central role in inflammatory responses. IL-17 R associates with IL-17 RC to form a signaling receptor complex for IL-17 and IL-17F. IL-17 R ligation promotes T cell activation and the production of IL-6, G-CSF, SCF, and...

Interleukin-17 is a pleotropic cytokine expressed by T cells. IL-17 binds to the IL-17 receptor (IL-17 R), which shares no homology with any other known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been detected...

IL-17R, also known as IL-17RA, is a widely expressed 120kD glycosylated type I protein that plays a central role in inflammatory responses. IL-17R associates with IL-17RC to form a signaling receptor complex for IL-17 and IL-17F. IL-17R ligation promotes T cell activation and the production of IL-6, G-CSF, SCF, and...

IL-17R, also known as IL-17RA, is a widely expressed 120kD glycosylated type I protein that plays a central role in inflammatory responses. IL-17R associates with IL-17RC to form a signaling receptor complex for IL-17 and IL-17F. IL-17R ligation promotes T cell activation and the production of IL-6, G-CSF, SCF, and...

Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte- associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+...

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by a subset of T helper cells that develops distinct from the Th1- and Th2- cell differentiation pathways. IL-17, also known as CTLA-8, stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly...

Source: , Two DNA sequences encoding the mature mouse IL-17A (Thr 22-Ala 158, Accession #Q62386) and mature mouse IL-17F (Arg 21-Ala 153, Accession # AAM77568) were expressed separately in E. coli. Molecular Mass: The recombinant mouse IL1-7A/IL-17F is a refolded disulfide-linked heterodimer of IL-17A and , IL-17F....

Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as...