Interleukin-17, His Tag, human recombinant (rHuIL-17-His)

Interleukin-17, His Tag, human recombinant (rHuIL-17-His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97276.2 2 µg - -

3 - 10 business days*

94.00€
97276.10 10 µg - -

3 - 10 business days*

208.00€
97276.1 1 mg - -

3 - 10 business days*

6,989.00€
 
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the... more
Product information "Interleukin-17, His Tag, human recombinant (rHuIL-17-His)"
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. (www.uniprot.org) Human recombinant Interleukin-17A produced in E.coli is a single, non-glycosylated, polypeptide chain containing 132 amino acids (fragment 24-155) having a molecular weight of 21.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. IL-17 is a proinflammatory cytokine produced by activated T-cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Keywords: CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, IL17A
Supplier: Biomol GmbH
Supplier-Nr: 97276

Properties

Application: Bioassay
Conjugate: No
Host: E.coli
Species reactivity: human
Purity: >95%
Format: Purified

Database Information

KEGG ID : K05489 | Matching products
UniProt ID : Q16552 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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