17 products were found matching "I8435-14"!

IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and...

Applications:, Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: I8435-12G is useful as a capture antibody in a sandwich ELISA for quantifying human IL-13 protein levels. I8435-12G antibody should be paired with biotinylated antibody, I8435-13A as the detection antibody, with...

Applications:, ELISA Detection: Useful as a detection antibody in a sandwich ELISA for quantifying human IL-13 protein levels.1,2 Biotinylated antibody should be paired with purified antibody (Cat. No. I8435-12G) or (Cat. No. I8435-05A) as the capture antibody, with purified recombinant human IL-13 as the standard.,...

Two type I membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein is now referred to as IL-13 Ra1 and is also known as CD213a. IL-13 Ra1 combines with IL-4 Ra to form a high affinity receptor complex...

Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and immune responses. IL-13Ra1 together with IL-4Ra forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells,...

This assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for IL-13 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-13 present is bound by the immobilized antibody. After washing away any unbound substances, an...

Sensitivity:, I8434-11E: Calibrator Diluent I <5pg/ml, I8434-11F: Calibrator Diluent II <5.1pg/ml, Range: 31.25-1000pg/ml , Specificity: Recognizes both natural and recombinant human IL-12. No significant crossreactivity with human IL-1a, IL-b IL-2, IL-3, IL-4, IL-5 IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12 p40...

IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and...

Application(s): , Functional Application: Blocks IL-13 induced proliferation., Optimal conditions must be determined individually for each, application.,

Applications:, ELISA Capture: Useful as a capture antibody in a sandwich ELISA for quantifying human IL-13 protein levels. Purified antibody should be paired with biotinylated antibody (Cat. No. I8435-13A) as the detection antibody, with purified recombinant human IL-13 as the standard., Immunofluorescence/Flow...

This assay applies the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific to IL-13 Ra2 has been pre-coated onto a microplate. Standards and samples are then added to the appropriate plate wells with a biotin-conjugated polyclonal antibody preparation specific for IL-13 Ra2 and...

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory...