9 products were found matching "I8434-31B"!

Applications:, Suitable for use in Direct ELISA, Western Blot and Immunoprecipitation. Other applications have not been tested. , Recommended Dilution: Direct ELISA: 1:5000 dilution will yield 0.5 O.D. using alkaline phosphatase conjugated rabbit anti-mouse Ig, Optimal dilutions to be determined by the researcher....

IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been...

Interleukin 12 (IL-12) is a heterodimeric cytokine composed of a p35 and a p40 subunit. The p35 subunit is unique to IL-12, while the p40 subunit also occurs in IL-23. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5ul labels 5 x 10e5 cells,...

Interleukin 12 (IL-12) is a heterodimeric cytokine composed of a p35 and a p40 subunit. The p35 subunit is unique to IL-12, while the p40 subunit also occurs in IL-23. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5ul labels 5 x 10e5 cells,...

Interleukin 12 (IL-12) is a heterodimeric cytokine composed of a p35 and a p40 subunit. The p35 subunit is unique to IL-12, while the p40 subunit also occurs in IL-23. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5ul labels 5 x 10e5 cells,...

Sensitivity:, I8434-11E: Calibrator Diluent I <5pg/ml, I8434-11F: Calibrator Diluent II <5.1pg/ml, Range: 31.25-1000pg/ml , Specificity: Recognizes both natural and recombinant human IL-12. No significant crossreactivity with human IL-1a, IL-b IL-2, IL-3, IL-4, IL-5 IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12 p40...

Interleukin-12 is produced by activated lymphocytes and macrophages. The properties of IL-12 include the stimulation of growth of activated T lymphocytes and the development of TH1 CD4 +ve cells and CD8 +ve cytotoxic T cells. Applications: ELISA: 0.15-0.30ug/ml, Western Blotting: 0.10-0.20ug/ml, Optimal working...

The biological activities of IL-12 are mediated through the high-affinity receptor complex composed of the IL-12 receptor b1 (IL-12 Rb1) and IL-12 receptor b2 (IL-12 Rb2) subunits. IL-12 Rb2 is a 130kD protein that interacts with p35 and is associated with Jak2. The expression of IL-12 Rb2 is absent on nai?ve T...

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably...