18 products were found matching "I8434.10"!

Source: Human Cells. MW :95.7kD. Recombinant Human EGFR is produced by our Mammalian expression system and the target gene encoding Leu25-Ser645 is expressed with a Fc tag at the C-terminus. EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for...

Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 18.7kD protein that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10, which may be inter-related, include inhibition of macrophage mediated cytokine...

Interleukin 12 (IL-12) is a heterodimeric cytokine composed of a p35 and a p40 subunit. The p35 subunit is unique to IL-12, while the p40 subunit also occurs in IL-23. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5ul labels 5 x 10e5 cells,...

Interleukin 12 (IL-12) is a heterodimeric cytokine composed of a p35 and a p40 subunit. The p35 subunit is unique to IL-12, while the p40 subunit also occurs in IL-23. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5ul labels 5 x 10e5 cells,...

Interleukin 12 (IL-12) is a heterodimeric cytokine composed of a p35 and a p40 subunit. The p35 subunit is unique to IL-12, while the p40 subunit also occurs in IL-23. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5ul labels 5 x 10e5 cells,...

Interleukin-12 is produced by activated B lymphocytes and macrophages. The properties of IL-12 include the stimulation of growth of activated T lymphocytes and the development of TH1 CD4 positive cells and CD8 positive cytotoxic T cells. Applications: Suitable for use in ELISA, Western Blot and Neutralization. Other...

Interleukin-12 is produced by activated B lymphocytes and macrophages. The properties of IL-12 include the stimulation of growth of activated T lymphocytes and the development of TH1 CD4 positive cells and CD8 positive cytotoxic T cells. Applications: Suitable for use in ELISA (direct), Western Blot and...

IL-12 is a heterodimer composed of subunits IL-12A p35 and IL-12B p40. Autocrine IL-12 is responsible for the differentiation of naive CD4+T cells into type 1 helper T cells (Th1) that produce interferon-_ (IFN-_). Expression of STAT 4, a signal transduction molecule important in cytokine-induced gene expression,...

IL-12 is a heterodimer composed of subunits IL-12A p35 and IL-12B p40. Autocrine IL-12 is responsible for the differentiation of naive CD4+T cells into type 1 helper T cells (Th1) that produce interferon-_ (IFN-_). Expression of STAT 4, a signal transduction molecule important in cytokine-induced gene expression,...

Interleukin 12 (IL-12) and interleukin 35 (IL-35) are heterodimeric cytokines composed of alpha and beta chains. IL-12 is composed of p35 and p40 subunits, while IL-35 is comprised of p35 paired with EBI-3. In mice, IL-35 is produced by FoxP3+ regulatory T cells and may function as an inhibitory cytokine to suppress...

Interleukin 12A is a novel signaling cytokine belonging to the Interleukin-6 protein superfamily. Interleukin-12 alpha chain precursor (IL-12A) is a 35kD subunit of disulfide-linked heterodimer of cytokine IL-12 and has a broad array of biological activities. Reports suggest that Interleukin 12A can act as a growth...

Interleukin 12, also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40kD (p40) subunit and a 35kD (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple...