7 products were found matching "I7663-22"!

The IL-1 system includes two agonists (IL-1a and IL-1b), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor. Applications: Suitable for use in Western Blots. Other applications not tested....

Interleukin-1 receptor II (IL-1 RII), also known as CD121b, is an immunoglobulin superfamily receptor that binds the pleiotropic cytokines, IL-1alpha and IL-1beta. It acts as an IL-1 antagonist because it has a short cytoplasmic domain and does not transduce IL-1 signals. IL-1 RII exists both as a transmembrane...

The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor. Applications: Can be used for Western Blot and Neutralization. Other...

The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 R I and IL-1 R II) and the IL-1 receptor accessory protein. The IL-1 R II is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signalling molecule which...

Applications:, ELISA: Useful as a capture antibody in a sandwich ELISA for quantifying mouse IL-2 protein levels. Purified antibody may be paired with biotinylated antibody (Cat. No. I7663-27M5) as the detection antibody, with purified recombinant mouse IL-2 as the standard. Or, conversely, biotinylated antibody may...

Interleukin-2 (IL-2), also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2...

Two distinct types of receptors that bind the pleiotropic cytokines IL-1a and IL-1b have been described. The IL-1 receptor Type I is an 80kD transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. IL-1 receptor Type II is a 68kD transmembrane protein found on B...