Interleukin-1 beta, His Tag, human recombinant (rHuIL-1-beta-His)

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag.