7 products were found matching "I7663-01"!

IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of...

Applications: , Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding...

Interleukin-1beta (IL-1beta), one of the major caspase-1 targets, is a multifunctional cytokine that is involved in a host of immune and proinflammatory responses. It is produced primarily by activated monocytes and macrophages. It signals through various adaptor proteins and kinases that lead to activation of...

Interleukin 1 alpha (IL-1 alpha) is synthesized as a 33kD precursor that mainly remains intracellular. Cleavage by calpain in keratinocytes, epithelial cells and endotoxin-stimulated peripheral blood mononuclear cells produces a 112aa, 16kD propeptide and a 159aa, 17kD mature protein. A nuclear localization site in...

IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of...

Rat IL-1 alpha is a 17.7kD cytokine which is produced by macrophages. IL-1 alpha is chemotactic for leukocytes and also contributes to the inflammatory response by its interactions with several other cell types. Interleukin 1alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor as...

IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. IL-1alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is also temporarily upregulated during bone formation and the...