59 products were found matching "I1000-01A.100"!

Pervanadate is a protein tyrosine phosphatase inhibitor that is commonly used to increase tyrosine phosphorylation in cells. When cells are treated with pervanadate for 30 minutes they undergo significant tyrosine phosphorylation, as shown by western blotting using anti-Phosphotyrosine. Confluent cultures of Jurkat...

Control Peptide for G4000-01G (ascites) and G4000-01D (affinity purified), An 18-aa peptide sequence near the amino terminus of rat GAD65 . Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. Glutamic acid decarboxylase (GAD, E.C.4.1.1.15) catalyzes the decarboxylation of glutamate...

Deleted in colorectal cancer (DCC) is a 170-190kD transmembrane glycoprotein that contains four Ig-like domains and six fibronectin type III repeats in its extracellular domain. DCC is expressed on axons during development where its binding to Netrin-1 regulates axon migration and myelination. It inhibits apoptosis...

Short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD, EC1.1.1.35) plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. It catalyzes the reversible dehydrogenation of 3-hydroxyacyl-CoAs to their corresponding 3-ketoacyl-CoAs with concomitant reduction of NAD to NADH and exerts it...

Notch signaling is activated upon engagement of the Notch receptor with its ligands, the DSL (delta, Serrate, Lag2) proteins of single-pass type I membrane proteins. The DSL proteins contain multiple EGF-like repeats and a DSL domain that is required for binding to Notch (1,2). Five DSL proteins have been identified...

The human p8 gene encodes a nuclear protein with strong mitogenic activity, which is expressed in the pancreas in response to acute pancreatitis. Response to TNF alpha and staurosporine-induced apoptosis is not modified by p8 expression. However, cells expressing p8 grow significantly and more rapidly. Applications:...

Rac1, belonging to the Rho small GTPase family, regulates the actin cytoskeleton but also other cellular processes. RAC1 have been shown to be involved in the regulation of cell-cell adhesion. Recombinant human RAC1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional...

RANTES, also known as CCL5, is expressed by circulating T cells and T cells in culture. RANTES is chemotactic for peripheral blood monocytes. Recommended Secondary Reagents: Sheep anti Rabbit IgG (Aff. Pur.): HRP , Applications:, ELISA: 0.5ug/ml, Western Blotting: 0.1-0.2ug/ml, Neutralization: 6-8ug/ml to yield one...

Syk, one of the well known protein tyrosine kinases, is widely expressed and plays an important role in intracellular signal transduction in hematopoietic cells (1-3). Syk has been shown to interact with immunoreceptor tyrosine-based activation motifs (ITAMs) located in the cytoplasmic domains of immune receptors...

USP7 (ubiquitin specific peptidase 7) is a nuclear protein belonging to the peptidase C19 family with a MATH domain and is known to cleave ubiquitin fusion protein substrates. It is a monomer that interacts with proteins like TP53, MDM2 and UBXN6 and also with Herpes virus 1 trans-acting transcriptional protein...

N-WASP is a ubiquitously expressed member of the WASP family of proteins. The 65 kD, 505 amino acid, N-WASP seems to play a central role as a node interconnecting various actin networks. Over the region used as immunogen, human N-WASP is greater than 98% identical to the corresponding mouse and canine protein...

LRMP is a 74-76kD protein that is associated with the ER. In contrast to its name, LRMP expression is not restricted to lymphoid cell types. Cells known to express LRMP include stomach chief cells, seminal vesicle cuboidal epithelium, neurons, germinal center B cells, cortical thymocytes, and cells of the taste...