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Interferon Regulatory Factor-2, His Tag, human recombinant (rHuIRF-2-His)
Product information "Interferon Regulatory Factor-2, His Tag, human recombinant (rHuIRF-2-His)"
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 133 amino acids (1-113) with a His Tag of 20 amino acids
Keywords:
IRF-2, IRF2, MAR, DKFZp686F0244, Interferon regulatory factor 2
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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