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Insulin-Like Growth Factor-I, human recombinant (rHuIGF-1)

ART NR.: 50356.100 (100 µg)
50356.1 (1 mg)

Hersteller: Biomol GmbH

Datenblatt

Anwendungen: Cell culture

Exprimiert in: E.coli

Ursprungs-Art: human

MW: 7.649 D

Lagerung: -20°C

Versand: +20°C

UniProt ID: P05019 | Suche mit UniProt ID

KEGG ID: K05459 | Suche mit KEGG ID

Schlagworte: Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF

50356.100

100 µg

72 €

50356.1

1 mg

395 €

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Bemerkungen: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 70 amino acids. The ED50, calculated by the dose-dependant proliferation of murine BALBC 3T3 cells (measured by H-thymidine uptake) is < 1.0 ng/ml.

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