- Search results for I7661-20J.10
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18 products were found matching "I7661-20J.10"!
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Item number: I7661-26C.100
The insulin receptor is a tyrosine kinase receptor that when bound to insulin, initiates multiple signal transduction pathways, including JNK, PI 3-kinase, Akt and PKC. Pharmacological intervention of these Insulin R-dependent pathways is of great interest for the treatment of insulin resistance, obesity and...
Keywords: | Anti-IR, Anti-CD220, EC=2.7.10.1, Anti-Insulin receptor subunit beta, Anti-Insulin receptor subunit alpha |
Application: | IP, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
901.00€
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Item number: I7661-26S.100
The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR...
Keywords: | EC=2.7.10.1, Anti-IR-related receptor, Anti-Insulin receptor-related protein, Anti-Insulin receptor-related protein beta... |
Application: | ELISA, IHC, WB |
Host: | Mouse |
Species reactivity: | human |
699.00€
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Item number: I7661-21M2.100
Type I insulin-like growth factor receptor (IGF-IR) is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues (1-3). Receptor autophosphorylation follows binding of the IGF-I and IGF-II ligands. Three tyrosine residues within the kinase...
Keywords: | EC=2.7.10.1, Anti-phospho-CD221, Anti-phospho-IGF-I receptor, Anti-phospho-Insulin-like growth factor 1 receptor,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 462.00€
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Item number: I7661-26K.10
Human INSR, Insulin receptor (beta) (GenBank Accession No. NM_000208). GST fusion protein containing the Mr 48kD cytoplasmic domain of the b-subunit of the human insulin receptor, residues 941-1343, expressed in a baculovirus expression system. Specific Activity: ~117 nmol/min/mg @ 25°C using poly(Glu:Tyr) 4:1...
Keywords: | INSR, CD220, EC=2.7.10.1, Insulin receptor, Insulin receptor subunit beta, Insulin receptor subunit alpha |
Application: | Enzyme assays |
955.00€
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Item number: I7661-22L.10
Biological actions of insulin are mediated by the insulin receptor (IR), a receptor tyrosine kinase that regulates multiple signaling pathways through activation of a series of phosphorylation cascades. The IR is a heterotetrameric protein consisting of two ligand-binding a subunits and two b subunits that each...
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
909.00€
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Item number: I7661-19M.200
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The...
Keywords: | EC=2.7.10.1, Anti-IGF-I receptor, Anti-Insulin-like growth factor 1 receptor, Anti-Insulin-like growth factor I receptor,... |
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
728.00€
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Item number: I7661-42H.10
Specificity: Integrin 3, also known as CD61, is a 130kD transmembrane glycoprotein that binds noncovalently in complexes with integrin alpha subunits (alphaIIb, alphav) to form the functional receptor that binds to specific extracellular matrix proteins (e.g., fibronectin, vitronectin, etc.). Integrin receptors are...
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
909.00€
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Item number: I7661-17W.100
IGFBP-rP10, also known as Kazal-type serine protease inhibitor domain-containing protein 1 and bone and odontoblast-expressed protein 1, belongs to the IFGBP superfamily. It is a 276 amino acid (aa) residue, 36 kD secreted protein that contains an N-terminal IGFBP domain, a Kazal-type serine protease inhibitor...
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | mouse |
916.00€
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Item number: I7661-17Y.100
IGFBP-rP10 (IGF binding protein-related protein 10, also Kazal-type serine protease inhibitor domain-contain protein 1 and BONO1) is a 37kD (predicted), secreted member of the IGFBP superfamily. It is expressed by osteoblasts and odontoblasts, is associated with regions of mineralization, and stimulates the...
Keywords: | Anti-FKSG28, Anti-KAZALD1, Anti-Kazal-type serine protease inhibitor domain-containing protein 1 |
Application: | ELISA, WB |
Host: | Sheep |
Species reactivity: | human |
962.00€
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Item number: I7661-18Q.100
Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding a subunits and two b...
Keywords: | EC=2.7.10.1, Anti-phospho-IGF-I receptor, Anti-phospho-Insulin-like growth factor 1 receptor, Anti-phospho-Insulin-like... |
Application: | IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 425.00€
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Item number: I7661-18U.100
Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding a subunits and two b...
Keywords: | EC=2.7.10.1, Anti-IGF-I receptor, Anti-Insulin-like growth factor 1 receptor, Anti-Insulin-like growth factor I receptor,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 425.00€
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Item number: I7661-18V.100
Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding a subunits and two b...
Keywords: | EC=2.7.10.1, Anti-IGF-I receptor, Anti-Insulin-like growth factor 1 receptor, Anti-Insulin-like growth factor I receptor,... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 425.00€
*