17 products were found matching "I7661-10"!

A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on Somatotropin. It is believed to be mainly active in adults in contrast to Insulin...

A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on Somatotropin. It is believed to be mainly active in adults in contrast to Insulin...

Unlike insulin, both IGF-I and IGF-II circulate in plasma tightly bound to specific binding proteins. Two major forms of IGFbinding proteins have been identified in human plasma, a low molecular weight form and a high molecular weight form. The low molecular weight IGF-binding protein (IGFBP1) is synthesized in...

The insulin like growth factors (IGFs) are the major growth- promoting factors in the plasma. IGFs are secreted by a variety of cells and exert a multitude of effects on cellular survival, growth and differentiation. The A and B domains of IGFs are identical to insulin. IGF initiates their biological action through...

Insulin Like Growth Factor-II (IGF-II) is a polypeptide growth factor which stimulates the proliferation of a wide range of cell types. Human IGF-II is a 7.5kD protein containing 67 amino acid residues. Biological Activity: The ED50, calculated by the dose-dependent induction of MCF-7 cell proliferation was found...

Unlike insulin, both IGF-I and IGF-II circulate in plasma tightly bound to specific binding proteins. Two major forms of IGF- binding proteins have been identified in human plasma, a low molecular weight form and a high molecular weight form. The low molecular weight IGF-binding protein (IGFBP1) is synthesized in...

IGFBP-rP10, also known as Kazal-type serine protease inhibitor domain-containing protein 1 and bone and odontoblast-expressed protein 1, belongs to the IFGBP superfamily. It is a 276 amino acid (aa) residue, 36 kD secreted protein that contains an N-terminal IGFBP domain, a Kazal-type serine protease inhibitor...

IGFBP-rP10 (IGF binding protein-related protein 10, also Kazal-type serine protease inhibitor domain-contain protein 1 and BONO1) is a 37kD (predicted), secreted member of the IGFBP superfamily. It is expressed by osteoblasts and odontoblasts, is associated with regions of mineralization, and stimulates the...

IGFBP-rP10 (IGF binding protein-related protein 10, also Kazal-type serine protease inhibitor domain-contain protein 1 and BONO1) is a 37kD (predicted), secreted member of the IGFBP superfamily. It is expressed by osteoblasts and odontoblasts, is associated with regions of mineralization, and stimulates the...

Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding a subunits and two b...

Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding a subunits and two b...

Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding a subunits and two b...