- Search results for Cay70271
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8 products were found matching "Cay70271"!
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Item number: Cay70271-5
Indomethacin is a potent but non-selective inhibitor of both COX-1 and COX-2 in sheep and humans. Structurally, indomethacin is a substituted indole acetic acid, wherein the carboxylate can be derivatized as an ester or amide. These derivatives show enhanced selectivity for the COX-2 isoform. For example, the IC50...
Keywords: | 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 1-heptyl ester |
Application: | COX-2 inhibitor |
CAS | 282728-47-6 |
MW: | 456 D |
From 34.00€
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Item number: Cay700277-1
Formulation: A lyophilized powder.
Application: | Kit component |
26.00€
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Item number: Cay700271-1
Synonyms: SET7/9 (human recombinant). Formulation: 300 µl of enzyme mixture.
Keywords: | SET7/9 (human recombinant) |
Application: | Kit component |
272.00€
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Item number: Cay70270-1
Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in...
Keywords: | 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid |
Application: | COX inhibitor |
CAS | 53-86-1 |
MW: | 357.8 D |
35.00€
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Item number: Cay70272-1
N-(2-phenylethyl)-indomethacin amide (N-2PIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively. It is over 400 times less potent as an inhibitor...
Keywords: | N-2PIA, N-(2-phenylethyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide |
Application: | COX-2 inhibitor |
CAS | 261766-32-9 |
MW: | 461 D |
From 24.00€
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Item number: Cay70273-1
Indomethacin is a potent but non-selective inhibitor of both COX-1 and COX-2 in sheep and humans. Structurally, indomethacin is a substituted indole acetic acid, wherein the carboxylate can be derivitized as an ester or amide. These derivatives show enhanced selectivity for the COX-2 isoform. For example, the IC50...
Keywords: | N-octyl-1-(4-chlorobenzoyl)-5-methoxy-1H-indole-3-acetamide |
Application: | COX-2 inhibitor |
CAS | 282728-65-8 |
MW: | 469 D |
From 34.00€
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Item number: Cay70274-1
N-(3-pyridyl)-indomethacin amide (N-3PyIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-3PyIA selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant...
Keywords: | N-3PyIA, N-(3-pyridyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide |
Application: | COX-2 inhibitor |
CAS | 261766-29-4 |
MW: | 433.9 D |
From 24.00€
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Item number: Cay70278-1
N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively. It is about 400 times less potent as an...
Keywords: | N-4AIA, N-(4-acetamidophenyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide |
Application: | COX-2 inhibitor |
CAS | 261766-23-8 |
MW: | 490 D |
From 24.00€
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