2 products were found matching "Cay13314-25"!

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Item number: Cay13142-5

PA-824 is an anti-tuberculosis (anti-TB) agent that is activated intracellularly via deazaflavin-dependent nitroreductase (Ddn) metabolism into a desnitro metabolite that kills M. tuberculosis by releasing reactive nitrogen species (RNS), including nitric oxide. It is active against replicating and non-replicating...

Keywords:	(S)-PA-824, (6S)-6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine
Application:	Antibacterial antibiotic (tuberculostatic)
CAS	187235-37-6
MW:	359.3 D

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Chelerythrine (chloride)

Item number: Cay11314-25

Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. Chelerythrine also inhibits Bcl-xL function (IC50 = 1.5 µM) by displacing Bax binding, inducing...

Keywords:	Broussonpapyrine chloride, NSC 646662, 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium, monochloride
Application:	Inhibitor of protein kinase C
CAS	3895-92-9
MW:	383.8 D

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