- Search results for Cay10009964-1
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10 products were found matching "Cay10009964-1"!
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Item number: Cay10009962-25
2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. 2-AG is hydrolyzed by the enzyme monoacylglycerol lipase, terminating its biological activity, and metabolism by cyclooxygenase-2 and lipoxygenases has...
Keywords: | (±)2-14,15-EG, (5Z,8Z,11Z)-13-(3-pentyl-2-oxiranyl)-5,8,11-tridecatrienoic acid, (±)2-hydroxy-1-(hydroxymethyl)ethyl ester |
Application: | Mitogen |
CAS | 848667-56-1 |
MW: | 394.5 D |
From 315.00€
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Item number: Cay10009965-25
VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN, IC50 = 35 nM in vitro). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular...
Keywords: | (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxo-v... |
Application: | PTEN inhibitor |
CAS | 476310-60-8 |
MW: | 415.2 D |
From 44.00€
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Item number: Cay10009986-5
Dimethoxycurcumin is a derivative of curcumin (Cay-81025) that has anti-inflammatory and antioxidant activities. It inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-gamma induced by concanavalin A (Cay-14951) in isolated human...
Keywords: | Di-O-methylcurcumin, 1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione |
Application: | Curcumin analog |
CAS | 160096-59-3 |
MW: | 396.4 D |
From 39.00€
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Item number: Cay10009864-5
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Cay-10011298) and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques....
Keywords: | 18:0/20:4-PC, 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine,... |
Application: | Bioactive lipid assays |
CAS | 35418-59-8 |
MW: | 810.1 D |
From 109.00€
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COVID-19 Research
Item number: Cay10007964-25
E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: | Loxistatin Acid, NSC 694279,... |
Application: | Cysteine protease inhibitor |
CAS | 76684-89-4 |
MW: | 314.4 D |
From 84.00€
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Item number: Cay10010994-1
Synonyms: SIRT1 (human recombinant).
Keywords: | SIRT1 (human recombinant) |
Application: | Kit component |
43.00€
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Item number: Cay10009796-5
CAY10602 is an activator of sirtuin 1 (SIRT1). It inhibits LPS-induced TNF-alpha release in THP-1 cells when used at concentrations of 20 and 60 µM. CAY10602 (5 µM) decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and malondialdehyde (MDA), in A549 lung and MDA-MB-231...
Keywords: | 1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine |
Application: | SIRT1 activator |
CAS | 374922-43-7 |
MW: | 418.4 D |
From 40.00€
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Item number: Cay10009594-5
Pseudomonas aeruginosa (P. aeruginosa) is a common pathogen affecting immunocompromised patients with acute diseases such as pneumonia and vasculitis or chronic diseases such as cystic fibrosis. It produces several phenazine toxic metabolites, the most predominant of which is a blue pigment, pyocyanin. Pyocyanin,...
Keywords: | Pyocyanine, Sanasin, Sanazin, 5-methyl-1(5H)-phenazinone |
Application: | Apoptosis inducer |
CAS | 85-66-5 |
MW: | 210.2 D |
From 78.00€
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Item number: Cay10009906-1
Origin: Animal/Goat, Animal/Bovine.
Application: | Cell-based assay component |
43.00€
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