25 products were found matching "Cay10009964-1"!

1 from 3 pages
No results were found for the filter!
(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol
(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

Item number: Cay10009962-25

2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. 2-AG is hydrolyzed by the enzyme monoacylglycerol lipase, terminating its biological activity, and metabolism by cyclooxygenase-2 and lipoxygenases has...
Keywords: (±)2-14,15-EG, (5Z,8Z,11Z)-13-(3-pentyl-2-oxiranyl)-5,8,11-tridecatrienoic acid, (±)2-hydroxy-1-(hydroxymethyl)ethyl ester
Application: Mitogen
CAS 848667-56-1
MW: 394.5 D
From 315.00€ *
Review
VO-OHpic (hydrate)
VO-OHpic (hydrate)

Item number: Cay10009965-25

VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN, IC50 = 35 nM in vitro). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular...
Keywords: (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxo-v...
Application: PTEN inhibitor
CAS 476310-60-8
MW: 415.2 D
From 44.00€ *
Review
SIRT1 Direct NAD+
SIRT1 Direct NAD+

Item number: Cay10010996-1

Application: Kit component
20.00€ *
Review
Dimethoxycurcumin
Dimethoxycurcumin

Item number: Cay10009986-5

Dimethoxycurcumin is a derivative of curcumin (Cay-81025) that has anti-inflammatory and antioxidant activities. It inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-gamma induced by concanavalin A (Cay-14951) in isolated human...
Keywords: Di-O-methylcurcumin, 1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione
Application: Curcumin analog
CAS 160096-59-3
MW: 396.4 D
From 39.00€ *
Review
1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC
1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

Item number: Cay10009864-5

1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Cay-10011298) and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques....
Keywords: 18:0/20:4-PC, 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine,...
Application: Bioactive lipid assays
CAS 35418-59-8
MW: 810.1 D
From 109.00€ *
Review
COVID-19 Research
E-64c
E-64c

Item number: Cay10007964-25

E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: Loxistatin Acid, NSC 694279,...
Application: Cysteine protease inhibitor
CAS 76684-89-4
MW: 314.4 D
From 84.00€ *
Review
SIRT1 (human recombinant) Direct Assay Reagent
SIRT1 (human recombinant) Direct Assay Reagent

Item number: Cay10010994-1

Synonyms: SIRT1 (human recombinant).
Keywords: SIRT1 (human recombinant)
Application: Kit component
43.00€ *
Review
CAY10602
CAY10602

Item number: Cay10009796-5

CAY10602 is an activator of sirtuin 1 (SIRT1). It inhibits LPS-induced TNF-alpha release in THP-1 cells when used at concentrations of 20 and 60 µM. CAY10602 (5 µM) decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and malondialdehyde (MDA), in A549 lung and MDA-MB-231...
Keywords: 1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
Application: SIRT1 activator
CAS 374922-43-7
MW: 418.4 D
From 40.00€ *
Review
Pyocyanin
Pyocyanin

Item number: Cay10009594-5

Pseudomonas aeruginosa (P. aeruginosa) is a common pathogen affecting immunocompromised patients with acute diseases such as pneumonia and vasculitis or chronic diseases such as cystic fibrosis. It produces several phenazine toxic metabolites, the most predominant of which is a blue pigment, pyocyanin. Pyocyanin,...
Keywords: Pyocyanine, Sanasin, Sanazin, 5-methyl-1(5H)-phenazinone
Application: Apoptosis inducer
CAS 85-66-5
MW: 210.2 D
From 78.00€ *
Review
Cell-Based Assay Blocking Solution
Cell-Based Assay Blocking Solution

Item number: Cay10009906-1

Origin: Animal/Goat, Animal/Bovine.
Application: Cell-based assay component
43.00€ *
Review
TrxR DTNB
TrxR DTNB

Item number: Cay10009096-1

Formulation: A crystalline solid.
Application: Kit component
20.00€ *
Review
Anti-Tryptophan Hydroxylase
Anti-Tryptophan Hydroxylase

Item number: Cay10009396-1

Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin. Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of...
Keywords: TPH
Application: WB, IHC (frozen)
Host: Sheep
Species reactivity: rabbit
564.00€ *
Review
1 from 3 pages