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Item number: Cay15243-5

Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. IWP-L6 is a potent inhibitor of PORCN (EC50 = 0.5 nM). It suppresses the...

Keywords:	PORCN Inhibitor III, Wnt Pathway Inhibitor XIX,...
Application:	Potent PORCN inhibitor
CAS	1427782-89-5
MW:	472.6 D

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