- Search results for Cay16800
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14 products were found matching "Cay16800"!
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Item number: Cay16800-10
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kgamma and PI3Kdelta (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kgamma and PI3Kdelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and...
Keywords: | Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone |
Application: | PI3K gamma / delta inhibitor |
CAS | 1201438-56-3 |
MW: | 416.9 D |
From 92.00€
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Item number: Cay16880-25
Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+. This nucleotide is a potent stimulator of adenylate cyclase. Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and...
Keywords: | 5'-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt |
Application: | Nonhydrolyzable GTP analog |
CAS | 64564-03-0 |
MW: | 545.9 D |
From 64.00€
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Item number: Cay16680-10
Unoprostone is an agonist of FP receptors (EC50 = 4.12 µM), an active metabolite the ocular hypotensive agent unoprostone isopropyl ester (Cay-16681), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It is formed from unoprostone isopropyl ester by hydrolysis. Intravitreal administered...
Keywords: | 13,14-dihydro-15-keto-20-ethyl PGF2alpha, 13,14-dihydro-15-keto-20-ethyl Prostaglandin F2alpha,... |
Application: | Bioactive lipid assays |
CAS | 120373-36-6 |
MW: | 382.5 D |
From 82.00€
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Item number: Cay16803-10
Luminol is a cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation. For example, HRP, combined with hydrogen peroxide as an activator, causes luminescent peroxidation of luminol. This reaction can be enhanced by certain phenol derivatives, such as p-substituted phenols. Luminol can also be oxidized,...
Keywords: | 3-Aminophthalhydrazide, NSC 5064, 5-amino-2,3-dihydro-1,4-phthalazinedione |
Application: | Chemiluminescence |
CAS | 521-31-3 |
MW: | 177.2 D |
From 60.00€
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Item number: Cay16802-10
CFSE is a fluorescent product of CFDA-SE (Cay-14456) cleavage by intracellular esterases. CFSE lacks the diacetate groups of CFDA-SE and, as a result, is less cell permeable. CFSE fluorescence is cytoplasmic, and it has excitation/emission maxima of 491 and 518 nm, respectively. It covalently couples to...
Keywords: | 5-Carboxyfluorescein NHS ester, 5-Carboxyfluorescein N-Succinimidyl ester, 5-Carboxyfluorescein-N-hydroxysuccinimide... |
Application: | Cell-permeable green fluorescent dye, Cell labeling |
CAS | 92557-80-7 |
MW: | 473.4 D |
From 121.00€
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Item number: Cay16804-10
Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole, a triazole derivative, is an inhibitor of brassinosteroid biosynthesis that has been developed in order to probe the myriad functions of...
Keywords: | beta-[(4-chlorophenyl)methyl]-alpha-methyl-alpha-phenyl-1H-1,2,4-triazole-1-ethanol |
Application: | Brassinosteroid biosynthesis inhibitor |
CAS | 224047-41-0 |
MW: | 327.8 D |
From 84.00€
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Item number: Cay16801-10
3-deoxy Galactosone is a 1,2-dicarbonyl compound originating from the degradation of galactose. It can be formed by Maillard or caramelization reactions. 3-deoxy Galactosone has been detected in various food items, including milk, apple juice, and beer, as well as in heat-sterilized dialysis fluids.Formal Name:...
Keywords: | 3-deoxy-D-threo-hexos-2-ulose |
Application: | Galactose degradation product, Maillard reaction product |
CAS | 4134-97-8 |
MW: | 162.1 D |
From 92.00€
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Item number: Cay16808-10
Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is dealkylated by these CYP isoforms to produce fluorescein benzyl ether, which is further hydrolyzed to fluorescein...
Keywords: | DBF, NSC 645658, 2-[3-oxo-6-(phenylmethoxy)-3H-xanthen-9-yl]-benzoic acid, phenylmethyl ester |
Application: | Fluorogenic probe, cytochrome P450 substrate |
CAS | 97744-44-0 |
MW: | 512.6 D |
From 60.00€
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Item number: Cay16805-10
Sulindac (Cay-10004386) is a non-steroidal anti-inflammatory drug that has an extensive epidemiology documenting reduced human colorectal cancer. In mouse models, sulindac was found not only to inhibit the enzymatic activity of polyp-associated COX-2, but also to downregulate the expression of colonic COX-2 protein...
Keywords: | Exisulind, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid |
Application: | Aldose reductase inhibitor |
CAS | 59864-04-9 |
MW: | 372.4 D |
From 62.00€
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Item number: Cay16807-50
(S)-(+)-Methoprene is a widely used insect growth regulator. It is remarkable for its lack of significant effects against a wide variety of mammals, although concerns remain for its effects on arthropod development. Methoprene acts as an activator of the juvenile hormone receptor, known as Methoprene-tolerant or Met...
Keywords: | Altosid(TM), d-Methoprene, ZR 2458, 11-methoxy-3,7S,11-trimethyl-2E,4E-dodecadienoic acid, 1-methylethyl ester |
Application: | TcMet activator, insect growth regulator |
CAS | 65733-16-6 |
MW: | 310.5 D |
From 43.00€
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Item number: Cay16860-500
Swainsonine is an indolizidine alkaloid naturally found in certain plants including locoweed that inhibits N-linked glycoside hydrolases, preventing the processing of asparagine-linked glycoproteins. It reversibly inhibits lysosomal alpha-mannosidase and Golgi alpha-mannosidase II (IC50 = 0.2 µM). Swainsonine is...
Keywords: | Tridolgosir, (1S,2R,8aR)-octahydro-indolizinetriol |
Application: | N-linked glycoside hydrolase inhibitor |
CAS | 72741-87-8 |
MW: | 173.2 D |
From 74.00€
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COVID-19 Research
Item number: Cay16833-100
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.2 nM). It reduces the formation of endothelin-1 (Cay-24127) and increases nitric oxide (NO) in human vascular endothelial cells when used at a concentration of 0.1 nM. Lisinopril inhibits the pressor response to angiotensin I in anesthetized...
Keywords: | MK-521, MK-522, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline |
Application: | ACE inhibitor |
CAS | 76547-98-3 |
MW: | 405.5 D |
From 15.00€
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