18 products were found matching "I8443-40P"!

Applications:, Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 2.5ug/ml, Western Blot: 1-2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only....

IL23 p19 (IL23A) is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of the IL23A subunit and the p40 subunit of interleukin 12 (IL12B). Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12,...

This monoclonal antibody recognizes human IL-23, a heterodimeric cytokine composed of the p40 subunit shared with IL-12 and a specific p19 subunit. This antibody recognizes heterodimeric IL-23, but does not react with the p40 subunit alone or recombinant IL-12(p70) when used as a capture antibody in ELISA. IL-23 is...

Synthetic peptide (DSLFRGLALTVQWES) corresponding to amino acids 560 to 574 of human IL-22R precursor. Blocking peptide for I8443-10 (polyclonal rabbit anti-human Interleukin 22R, CT antibody). , Storage and Stability:, May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store...

IL-23 R is an IL-23-specific binding protein that associates with IL-12 R beta 1 to form a functional heterodimeric receptor complex. This complex mediates biological activities that are similar to, but distinct from those induced by IL-12. IL-23 R is expressed by Th1 and NK cells. Applications: Suitable for use in...

Interleukin 23 is a ~21kD heterodimeric cytokine structurally related to IL-12. IL-23 is composed of a p19 subunit encoded by the IL23A gene, and a p40 subunit of interleukin-12 (IL12B). IL-23 is expressed mainly by activated macrophages and dendritic cells, and plays an important role in bridging innate and...

Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C....

IL-23 p19 is an 18-20kD (estimated) member of the IL-6 superfamily of molecules. It is disulfide-bonded to p40 to form IL-23. IL-23 is secreted by immune-related cell types such as keratinocytes, dendritic cells, macrophages, microglia and monocytes, often following TLR stimulation. It appears to drive Th17 cell...

IL-23 p19 is an 18-20kD (estimated) member of the IL-6 superfamily of molecules. It is disulfide-bonded to p40 to form IL-23. IL-23 is secreted by immune-related cell types such as keratinocytes, dendritic cells, macrophages, microglia and monocytes, often following TLR stimulation. It appears to drive Th17 cell...

IL-23R is an IL-23-specific binding protein that associates with IL-12 Rb1 to form a functional heterodimeric receptor complex. This complex mediates biological activities that are similar to, but distinct from, those induced by IL-12. IL-23R is expressed by Th1 and NK cells. Applications: Suitable for use in Flow...

Interleukin 23 (IL23) is a heterodimeric cytokine composed of two disulfidelinked subunits, a p19 subunit that is unique to IL23, and a p40 subunit that is shared with IL12 (1 5). The functional IL23 receptor complex consists of two receptor subunits, the IL12 receptor beta 1 subunit (IL12Rb1) and the IL23 specific...

Recently, IL-23 is a heterodimeric cytokine that shares biological properties with proinflammatory cytokines has been discovered. IL-23 is composed of the IL-12p40 soluble receptor subunit and a novel cytokine-like subunit related to IL-12p35, termed p19. IL-23 mediates it cellular function by binding to IL-23...