IL-6 (mouse):Fc (mouse) (rec.) (non-lytic) MultiPack

IL-6 (mouse):Fc (mouse) (rec.) (non-lytic) MultiPack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-MF-12006-C050 50 µg - -

3 - 9 business days*

303.00€
 
The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion... more
Product information "IL-6 (mouse):Fc (mouse) (rec.) (non-lytic) MultiPack"
The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin 6 (IL-6) is a pleiotropic alphahelical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22 kDa 28kDa phosphorylated and variably glycosylated molecule. Human IL6 is equally active on mouse and rat cells. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130).
Keywords: Il6, IL-6, Interleukin-6, Interleukin HP-1, B-cell hybridoma growth factor
Supplier: Chimerigen Laboratories
Supplier-Nr: MF-12006

Properties

Application: Bioassays
Conjugate: No
Host: Hamster cells
Species reactivity: mouse
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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