IL-6 (human):Fc (human) (rec.) (non-lytic) MultiPack

IL-6 (human):Fc (human) (rec.) (non-lytic) MultiPack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HF-22006-C050 50 µg - -

3 - 9 business days*

248.00€
 
The extracellular domain of human IL-6 (aa 30-212) is fused at the C-terminus to the Fc portion... more
Product information "IL-6 (human):Fc (human) (rec.) (non-lytic) MultiPack"
The extracellular domain of human IL-6 (aa 30-212) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin 6 (IL-6) is a pleiotropic alphahelical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22 kDa 28kDa phosphorylated and variably glycosylated molecule. Human IL6 is equally active on mouse and rat cells. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130).
Keywords: CDF, IL6, IL-6, BSF-2, IFNB2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, B-cell stimulatory factor 2
Supplier: Chimerigen Laboratories
Supplier-Nr: HF-22006

Properties

Application: Bioassays
Conjugate: No
Host: Hamster cells
Species reactivity: human
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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